Sildenafil is usually a potent and selective inhibitor of cGMP-distinct phosphodiesterase variety five (PDE5), that is liable for degradation of cGMP inside the corpus cavernosum. The molecular framework of sildenafil is similar to that of cGMP and functions for a competitive binding agent of PDE5 from the corpus cavernosum, leading to extra cGMP and improved penile reaction to sexual stimulation.
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Viagra'nın etki mekanizmasının temelinde, cGMP advertisementı verilen bir molekülün yıkımını engelleyerek penisteki kan damarlarının gevşemesi ve dolayısıyla kan akışının artması yatmaktadır.
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